Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from Dirofilaria immitis in an In Vitro Endothelial Model

Heartworm disease, caused by Dirofilaria immitis, is a vector-borne zoonotic disease, (mainly affecting canids and felids) causing chronic vascular and pulmonary pathology in its early stages, which worsens with parasite load and/or death of adult worms in the pulmonary artery or right heart cavity, and can be fatal to the host.Angiogenesis is a me

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European social model and challenges of globalization: searching the ways of balancing of the needs of the economy and societ

The features of the fundamental models of social policy in the EU and social procection system as one of its Shelving Unit mechanisms has been characterized.The changes in the division of responsibility between the subjects of social partnership in providing social protection is analyzed.Special attention paid to the increasing socio-economic contr

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A model of symptomatic infantile spasms syndrome

Infantile spasms are characterized by age-specific expression of epileptic spasms and hypsarrhythmia and often result in significant cognitive impairment.Other epilepsies or autism often ensue especially in symptomatic IS (SIS).Cortical or subcortical damage, including white matter, have been implicated in the pathogenesis of SIS.To generate a mode

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Molecular characterization of three peroxiredoxin genes in Portunus pelagicus expressed in response to Vibrio alginolyticus challenge

Portunus pelagicus inhabits coastal muddy or sandy seabed, and are often exposed to rotten sewage containing a large number of bacteria.In this study, RT-PCR technology was used to clone peroxiredoxin (prx) genes prx1, prx3 and prx6 of P.pelagicus.Genes expressed in normal tissue, gills and hepatopancreas Mirror Hardware after Vibrio alginolyticus

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